Mosig Lab
Publications

Publication list

All peer-reviewed articles, reviews and book chapters, each shown with its full author line. The complete record is also available on ORCID.

Original articles (peer-reviewed) (68)

2026
Pomraenke, M., Greiser, J., Perkas, O., Zehner, L., Wegner, V.D., Gaßler, M., Mosig, A.S., Huebner, K., Schneider-Stock, R., Ghaffari-Tabrizi-Wizsy, N., Freesmeyer, M. (2026). Expanding CAM models, in vivo PET/CT imaging of cancer xenografts on the ostrich CAM. ACS Applied Bio Materials. DOI ↗ Allwang, M., Wipplinger, M., Akbarimoghaddam, P., Alonso-Román, R., Cseresnyes, Z., Dietschmann, A., Wegner, V., Feile, A., Bachelot, Y., Warschinke, M., Hassan, M.I.A., Mittag, S., Huber, O., Hube, B., Gresnigt, M.S., Figge, M.T., Mosig, A.S. (2026). Human colitis-on-chip model reveals dual roles of butyrate in epithelial and macrophage defense against Candida albicans tissue invasion. Small (Weinheim, Germany), e00074. DOI ↗ Kaden, T., Allwang, M., Stallhofer, J., Graf, K., Raasch, M., Mosig, A.S. (2026). Secondary bile acid lithocholic acid ameliorates colitis-like inflammation in a human intestine-on-chip system. Frontiers in Immunology, 17, 1761539. DOI ↗ Wegner, V.D., Warschinke, M., Ben Brahim, I., Feile, A., Huber, K.E., Mosig, A.S. (2026). Modeling Clostridioides difficile toxin pathogenesis and antiserum protection in an immunocompetent intestine-on-chip platform. Scientific Reports, 16(1), 9233. DOI ↗
2025
Gauthier, L.*, Koceva, H.*, Bachelot, Y., Koutstaal, R., van Kasteren, P., Figge, M.T., Eggeling, C., Mosig, A.S. (2025). Generation of an induced pluripotent stem cell-derived alveolar type II in vitro model to study influenza A virus infection and drug treatments. Advanced Healthcare Materials, e05141. (* contributed equally). DOI ↗ Kapitan, M., Niemiec, M.J., Swidergall, M., Millet, N., Brandt, P., Chowdhury, E., Hoffmann, F., Höring, S., Lange, A., Veleba, M., Nietzsche, S., Mosig, A.S., Löffler, B., Kline, K., Vylkova, S., Jacobsen, I.D. (2025). Synergistic cross-kingdom host cell damage with Candida albicans relies on Enterococcus faecalis cytolysin. Proceedings of the National Academy of Sciences, 122(46), e2505310122. DOI ↗ Gheitasi, R., Weiss, D., Müller, M.M., Sommer, K., Roell, D., Mosig, A.S., Pletz, M.W., Makarewicz, O. (2025). Staphylococcus aureus biofilm-associated component PNAG stimulates the secretion of the immunomodulatory chemokine CXCL10 via Dectin-1 signaling. Communications Biology, 8(1), 1136. DOI ↗ Wegner, V.D., Feile, A., Alb, M., Hudecek, M., Hewitt, P., Mosig, A.S. (2025). Short-chain fatty acids modulate anti-ROR1 CAR T-cell function and exhaustion in an intestinal adenocarcinoma-on-chip model. Advanced Healthcare Materials, 14(13), e2405003. DOI ↗
2024
Liu, H., Yin, G., Kohlhepp, M.S., Schumacher, F., Hundertmark, J., Abdelwahab Hassan, M., Heymann, F., Puengel, T., Kleuser, B., Mosig, A.S., Tacke, F., Guillot, A. (2024). Dissecting pathomechanisms and therapeutic responses of steatotic liver disease using primary mouse liver and blood cells in a liver-on-a-chip model. Advanced Science, 11(30), e2403516. DOI ↗ Feile, A., Wegner, V., Mosig, A.S. (2024). Immunocompetent intestine-on-chip model for analyzing gut mucosal immune responses. Journal of Visualized Experiments (JoVE), (207), e66603. DOI ↗ Koceva, H., Amiratashani, M., Rennert, K., Mosig, A.S. (2024). Immunocompetent alveolus-on-chip model for studying alveolar mucosal immune responses. Journal of Visualized Experiments (JoVE), (207), e66602. DOI ↗ Ehle, C., Iyer-Bierhoff, A., Wu, Y., Xing, S., Kiehntopf, M., Mosig, A.S., Godmann, M., Heinzel, T. (2024). Repression of HNF4A enables transcriptomic reprogramming during the hepatic acute-phase response. Communications Biology, 7(1), 589. DOI ↗ Kaden, T.*, Alonso-Román, R.*, Akbarimoghaddam, P.*, Mosig, A.S., Graf, K., Raasch, M., Hoffmann, B., Figge, M.T., Hube, B., Gresnigt, M.S. (2024). Modeling of intravenous caspofungin administration using an intestine-on-chip reveals altered Candida albicans microcolonies and pathogenicity. Biomaterials, 307, 122525. (* contributed equally). DOI ↗ Lucchetti, M., Kehinde Oluwasegun, A., Grandmougin, L., Jäger, C., Perez-Escriva, P., Letellier, E., Mosig, A.S., Wilmes, P. (2024). An organ-on-chip platform for simulating drug metabolism along the gut-liver axis. Advanced Healthcare Materials, 13(10), e2303943. DOI ↗ Roth, A., Tannert, A., Ziller, N., Eiserloh, A., Göhrig, B., Guliev, R.R., Gonzalez Vazquez, M.J., Naumann, M., Mosig, A.S., Stengel, S., Heutelbeck, A.R.R., Neugebauer, U. (2024). Quantification of polystyrene uptake by different cell lines using fluorescence microscopy and label-free visualization of intracellular polystyrene particles by Raman microspectroscopic imaging. Cells, 13(5), 454. DOI ↗ Kowalczuk, K., Wegner, V., Mosig, A.S.*, Schacher, F.H.* (2024). Tailoring the degradation time of polycationic PEG-based hydrogels towards dynamic cell culture matrices. ACS Applied Bio Materials, 7(4), 2521 to 2533. (* shared senior authorship). DOI ↗ Kowalczuk, K., Dasgupta, A., Páez Larios, F., Ulrich, H.F., Wegner, V., Brendel, J.C., Eggeling, C., Mosig, A.S., Schacher, F.H. (2024). Self-degrading multifunctional PEG-based hydrogels, tailormade substrates for cell culture. Macromolecular Bioscience, 24(5), e2300383. DOI ↗ Kowalczuk, K., Mons, P.J., Ulrich, H.F., Wegner, V.D., Brendel, J.C., Mosig, A.S., Schacher, F.H. (2024). Asymmetric block extension of star-shaped [PEG-SH]4 toward poly(dehydroalanine)-functionalized PEG hydrogels for catch and release of charged guest molecules. Macromolecular Bioscience, 24(4), e2300230. DOI ↗
2023
Fahrner, R., Gröger, M., Settmacher, U., Mosig, A.S. (2023). Functional integration of natural killer cells in a microfluidically perfused liver-on-a-chip model. BMC Research Notes, 16(1), 285. DOI ↗ Kaden, T., Graf, K., Rennert, K., Li, R., Mosig, A.S., Raasch, M. (2023). Evaluation of drug-induced liver toxicity of trovafloxacin and levofloxacin in a human microphysiological liver model. Scientific Reports, 13(1), 13338. DOI ↗
2022
Siwczak, F., Cseresnyes, Z., Hassan, M.I.A., Aina, K.O., Carlstedt, S., Sigmund, A., Gröger, M., Surewaard, B.G.J., Werz, O., Figge, M.T., Tuchscherr, L., Löffler, B., Mosig, A.S. (2022). Human macrophage polarization determines bacterial persistence of Staphylococcus aureus in a liver-on-chip-based infection model. Biomaterials, 287, 121632. DOI ↗ Hoang, T.N.M., Cseresnyes, Z., Hartung, S., Blickensdorf, M., Saffer, C., Rennert, K., Mosig, A.S., von Lilienfeld-Toal, M., Figge, M.T. (2022). Invasive aspergillosis-on-chip, a quantitative treatment study of human Aspergillus fumigatus infection. Biomaterials, 283, 121420. DOI ↗ Ehsani, M., Bartsch, S., Rasa, S.M.M., Dittmann, J., Pungsrinont, T., Neubert, L., Huettner, S.S., Kotolloshi, R., Schindler, K., Ahmad, A., Mosig, A.S., Adam, L., Ori, A., Neri, F., Berndt, A., Grimm, M.O., Baniahmad, A. (2022). The natural compound atraric acid suppresses androgen-regulated neo-angiogenesis of castration-resistant prostate cancer through angiopoietin 2. Oncogene, 41(23), 3263 to 3277. DOI ↗
2021
Neukirch, K., Alsabil, K., Dinh, C.P., Bilancia, R., Raasch, M., Ville, A., Cerqua, I., Viault, G., Bréard, D., Pace, S., Temml, V., Brunner, E., Jordan, P.M., Marques, M.C., Loeser, K., Gollowitzer, A., Permann, S., Gerstmeier, J., Lorkowski, S., Stuppner, H., Garscha, U., Rodrigues, T., Bernardes, G.J.L., Schuster, D., Séraphin, D., Richomme, P., Rossi, A., Mosig, A.S., Roviezzo, F., Werz, O., Helesbeux, J.J., Koeberle, A. (2021). Exploration of long-chain vitamin E metabolites for the discovery of a highly potent, orally effective, and metabolically stable 5-LOX inhibitor that limits inflammation. Journal of Medicinal Chemistry, 64(15), 11496 to 11526. DOI ↗ Deinhardt-Emmer, S., Böttcher, S., Häring, C., Giebeler, L., Henke, A., Zell, R., Jungwirth, J., Jordan, P.M., Werz, O., Hornung, F., Brandt, C., Marquet, M., Mosig, A.S., Pletz, M.W., Schacke, M., Rödel, J., Heller, R., Nietzsche, S., Löffler, B., Ehrhardt, C. (2021). SARS-CoV-2 causes severe epithelial inflammation and barrier dysfunction. Journal of Virology, 95(10), e00110-21. DOI ↗ Heinze, K., Hölzer, M., Ungelenk, M., Gerth, M., Thomale, J., Heller, R., Morden, C.R., McManus, K.J., Mosig, A.S., Dürst, M., Runnebaum, I.B., Häfner, N. (2021). RUNX3 transcript variants have distinct roles in ovarian carcinoma and differently influence platinum sensitivity and angiogenesis. Cancers, 13(3), 476. DOI ↗ Gresing, L.J., Radon, P., Friedrich, R.P., Zahn, D., Raasch, M., Mosig, A.S., Dutz, S., Alexiou, C., Wiekhorst, F., Hochhaus, A., Clement, J.H. (2021). Negatively charged magnetic nanoparticles pass the blood-placenta barrier under continuous flow conditions in a time-dependent manner. Journal of Magnetism and Magnetic Materials, 521, 167535. DOI ↗
2020
Diederich, B., Lachmann, R., Carlstedt, S., Marsikova, B., Wang, H., Uwurukundu, X., Mosig, A.S., Heintzmann, R. (2020). UC2, a versatile and customizable low-cost 3D-printed optical open-standard for microscopic imaging. Nature Communications, 11(1), 5979. DOI ↗ Tansi, F.L., Rüger, R., Böhm, C., Steiniger, F., Raasch, M., Mosig, A.S., Kontermann, R.E., Teichgräber, U.K., Fahr, A., Hilger, I. (2020). Rapid target binding and cargo release of activatable liposomes bearing HER2 and FAP single-chain antibody fragments reveal potentials for image-guided delivery to tumors. Pharmaceutics, 12(10), 972. DOI ↗ Schicke, E., Cseresnyes, Z., Rennert, K., Vau, V., Haupt, K.F., Hornung, F., Nietzsche, S., Siwczak, F., Schmidtke, M., Glück, B., Koch, M., Schacke, M., Heller, R., Mosig, A.S., Figge, M.T., Ehrhardt, C., Löffler, B., Deinhardt-Emmer, S. (2020). Staphylococcus aureus lung infection results in down-regulation of surfactant protein-A mainly caused by pro-inflammatory macrophages. Microorganisms, 8(4), 577. DOI ↗ Spengler, K., Kryeziu, N., Große, S., Mosig, A.S., Heller, R. (2020). VEGF triggers transient induction of autophagy in endothelial cells via AMPKα1. Cells, 9(3), 687. DOI ↗ Deinhardt-Emmer, S., Rennert, K., Schicke, E., Cseresnyes, Z., Windolph, M., Nietzsche, S., Heller, R., Siwczak, F., Haupt, K.F., Carlstedt, S., Schacke, M., Figge, M.T., Ehrhardt, C., Löffler, B., Mosig, A.S. (2020). Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model. Biofabrication, 12(2), 025012. DOI ↗ Schubert, M., Becher, S., Wallert, M., Maeß, M.B., Abhari, M., Rennert, K., Mosig, A.S., Große, S., Heller, R., Grün, M., Lorkowski, S. (2020). The peroxisome proliferator-activated receptor (PPAR)-γ antagonist 2-chloro-5-nitro-N-phenylbenzamide (GW9662) triggers perilipin 2 expression via PPARδ and induces lipogenesis and triglyceride accumulation in human THP-1 macrophages. Molecular Pharmacology, 97(3), 212-225. DOI ↗
2019
Graf, K., Last, A., Gratz, R., Allert, S., Linde, S., Westermann, M., Gröger, M., Mosig, A.S., Gresnigt, M.S., Hube, B. (2019). Keeping Candida commensal, how lactobacilli antagonize pathogenicity of Candida albicans in an in vitro gut model. Disease Models & Mechanisms, 12(9), dmm039719. DOI ↗ Maurer, M., Gresnigt, M.S., Last, A., Wollny, T., Berlinghof, F., Pospich, R., Cseresnyes, Z., Medyukhina, A., Graf, K., Gröger, M., Raasch, M., Siwczak, F., Nietzsche, S., Jacobsen, I.D., Figge, M.T., Hube, B., Huber, O., Mosig, A.S. (2019). A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies. Biomaterials, 220, 119396. DOI ↗ Blaurock-Möller, N., Gröger, M., Siwczak, F., Dinger, J., Schmerler, D., Mosig, A.S.*, Kiehntopf, M.* (2019). CAAP48, a new sepsis biomarker, induces hepatic dysfunction in an in vitro liver-on-chip model. Frontiers in Immunology, 10, 273. (* shared senior authorship). DOI ↗
2018
Ryabchykov, O., Bräutigam, K., Galler, K., Neugebauer, U., Mosig, A.S., Bocklitz, T., Popp, J. (2018). Characterization of the unique human liver cell line HepaRG by Raman microspectroscopy. Journal of Raman Spectroscopy, 49(6), 935-942. DOI ↗ Leonhardt, J., Große, S., Marx, C., Siwczak, F., Stengel, S., Bruns, T., Bauer, R., Kiehntopf, M., Williams, D.L., Wang, Z.Q., Mosig, A.S., Weis, S., Bauer, M., Heller, R. (2018). Candida albicans β-glucan differentiates human monocytes into a specific subset of macrophages. Frontiers in Immunology, 9, 2818. DOI ↗ Pein, H., Ville, A., Pace, S., Temml, V., Garscha, U., Raasch, M., Alsabil, K., Viault, G., Dinh, C.P., Guilet, D., Troisi, F., Neukirch, K., König, S., Bilancia, R., Waltenberger, B., Stuppner, H., Wallert, M., Lorkowski, S., Weinigel, C., Rummler, S., Birringer, M., Roviezzo, F., Sautebin, L., Helesbeux, J.J., Séraphin, D., Mosig, A.S., Schuster, D., Rossi, A., Richomme, P., Werz, O., Koeberle, A. (2018). Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase. Nature Communications, 9(1), 3834. DOI ↗ Heinze, K., Kritsch, D., Mosig, A.S., Dürst, M., Häfner, N., Runnebaum, I.B. (2018). Functional analyses of RUNX3 and CaMKIIα in ovarian cancer cell lines reveal tumor-suppressive functions for CaMKIIα and dichotomous roles for RUNX3 transcript variants. International Journal of Molecular Sciences, 19(1), 253. DOI ↗ Gröger, M., Dinger, J., Kiehntopf, M., Peters, F.T., Rauen, U., Mosig, A.S. (2018). Preservation of cell structure, metabolism, and biotransformation activity of liver-on-chip organ models by hypothermic storage. Advanced Healthcare Materials, 7(2), 1700616. DOI ↗
2017
Fahrner, R., Möller, A., Press, A.T., Kortgen, A., Kiehntopf, M., Rauchfuss, F., Settmacher, U., Mosig, A.S. (2017). Short-term treatment with taurolidine is associated with liver injury. BMC Pharmacology & Toxicology, 18(1), 61. DOI ↗ Rennert, K., Nitschke, M., Wallert, M., Keune, N., Raasch, M., Lorkowski, S., Mosig, A.S. (2017). Thermo-responsive cell culture carrier, effects on macrophage functionality and detachment efficiency. Journal of Tissue Engineering, 8, 2041731417726428. DOI ↗ Kritsch, D., Hoffmann, F., Steinbach, D., Jansen, L., Mary Photini, S., Gajda, M., Mosig, A.S., Sonnemann, J., Peters, S., Melnikova, M., Thomale, J., Dürst, M., Runnebaum, I.B., Häfner, N. (2017). Tribbles 2 mediates cisplatin sensitivity and DNA damage response in epithelial ovarian cancer. International Journal of Cancer, 141(8), 1600 to 1614. DOI ↗ Mann, A., Pelz, T., Rennert, K., Mosig, A.S., Decker, M., Lupp, A. (2017). Evaluation of HepaRG cells for the assessment of indirect drug-induced hepatotoxicity using INH as a model substance. Human Cell, 30(4), 267-278. DOI ↗ Thomas, L., Rao, Z., Gerstmeier, J., Raasch, M., Weinigel, C., Rummler, S., Menche, D., Müller, R., Pergola, C., Mosig, A.S., Werz, O. (2017). Selective upregulation of TNFα expression in classically-activated human monocyte-derived macrophages (M1) through pharmacological interference with V-ATPase. Biochemical Pharmacology, 130, 71-82. DOI ↗ Pergola, C., Schubert, K., Pace, S., Ziereisen, J., Nikels, F., Scherer, O., Hüttel, S., Zahler, S., Vollmar, A.M., Weinigel, C., Rummler, S., Müller, R., Raasch, M., Mosig, A.S., Koeberle, A., Werz, O. (2017). Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy. Scientific Reports, 7, 41434. DOI ↗ Schüler, R., Osterhoff, M.A., Frahnow, T., Seltmann, A.C., Busjahn, A., Kabisch, S., Xu, L., Mosig, A.S., Spranger, J., Möhlig, M., Hornemann, S., Kruse, M., Pfeiffer, A.F. (2017). High-saturated-fat diet increases circulating angiotensin-converting enzyme, which is enhanced by the rs4343 polymorphism defining persons at risk of nutrient-dependent increases of blood pressure. Journal of the American Heart Association, 6(1), e004465. DOI ↗ Gröger, M., Lange, M., Rennert, K., Kaschowitz, T., Plettenberg, H., Hoffmann, M., Mosig, A.S. (2017). Novel approach for the prediction of cell densities and viability in standardized translucent cell culture biochips with near infrared spectroscopy. Engineering in Life Sciences, 17(5), 585-593. DOI ↗
2016
Englert, C., Trützschler, A.K., Raasch, M., Bus, T., Borchers, P., Mosig, A.S.*, Traeger, A.*, Schubert, U.S.* (2016). Crossing the blood-brain barrier, glutathione-conjugated poly(ethylene imine) for gene delivery. Journal of Controlled Release, 241, 1-12. (* shared senior authorship). DOI ↗ Raasch, M., Rennert, K., Jahn, T., Gärtner, C., Schönfelder, G., Huber, O., Seiler, A.E., Mosig, A.S. (2016). An integrative microfluidically supported in vitro model of an endothelial barrier combined with cortical spheroids simulates effects of neuroinflammation in neocortex development. Biomicrofluidics, 10(4), 044102. DOI ↗ Rennert, K., Heisig, K., Groeger, M., Wallert, M., Funke, H., Lorkowski, S., Huber, O., Mosig, A.S. (2016). Recruitment of CD16(+) monocytes to endothelial cells in response to LPS-treatment and concomitant TNF release is regulated by CX3CR1 and interfered by soluble fractalkine. Cytokine, 83, 41-52. DOI ↗ Gröger, M., Rennert, K., Giszas, B., Weiß, E., Dinger, J., Funke, H., Kiehntopf, M., Peters, F.T., Lupp, A., Bauer, M., Claus, R.A., Huber, O., Mosig, A.S. (2016). Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model. Scientific Reports, 6, 21868. DOI ↗ Rennert, K., Otto, P., Funke, H., Huber, O., Tomaso, H., Mosig, A.S. (2016). A human macrophage-hepatocyte co-culture model for comparative studies of infection and replication of Francisella tularensis LVS strain and subspecies holarctica and mediasiatica. BMC Microbiology, 16, 2. DOI ↗ Press, A.T., Ungelenk, L., Rinkenauer, A.C., Gröger, M., Lehmann, F., Mosig, A.S., Schubert, U.S., Clemens, M.G., Bauer, M. (2016). A new fluorescent dye for cell tracing and mitochondrial imaging in vitro and in vivo. Journal of Biophotonics, 9(9), 888-900. DOI ↗
2015
Rennert, K., Steinborn, S., Gröger, M., Ungerböck, B., Jank, A.M., Ehgartner, J., Nietzsche, S., Dinger, J., Kiehntopf, M., Funke, H., Peters, F.T., Lupp, A., Gärtner, C., Mayr, T., Bauer, M., Huber, O., Mosig, A.S. (2015). A microfluidically perfused three-dimensional human liver model. Biomaterials, 71, 119-131. DOI ↗ Gögebakan, Ö., Osterhoff, M.A., Schüler, R., Pivovarova, O., Kruse, M., Seltmann, A.C., Mosig, A.S., Rudovich, N., Nauck, M., Pfeiffer, A.F. (2015). GIP increases adipose tissue expression and blood levels of MCP-1 in humans and links high energy diets to inflammation, a randomised trial. Diabetologia, 58(8), 1759 to 1768. DOI ↗ Rinkenauer, A.C., Press, A.T., Raasch, M., Pietsch, C., Schweizer, S., Schwörer, S., Rudolph, K.L., Mosig, A.S., Bauer, M., Traeger, A., Schubert, U.S. (2015). Comparison of the uptake of methacrylate-based nanoparticles in static and dynamic in vitro systems as well as in vivo. Journal of Controlled Release, 216, 158-168. DOI ↗ Maeß, M., Keller, A.A., Rennert, K., Mosig, A.S., Lorkowski, S. (2015). Optimization of the transfection of human THP-1 macrophages by application of Nunc UpCell technology. Analytical Biochemistry, 479, 40-42. DOI ↗ Raasch, M., Rennert, K., Jahn, T., Peters, S., Henkel, T., Huber, O., Schulz, I., Becker, H., Lorkowski, S., Funke, H., Mosig, A.S. (2015). Microfluidically supported biochip design for culture of endothelial cell layers with improved perfusion conditions. Biofabrication, 7(1), 015013. DOI ↗
2014
Press, A.T., Traeger, A., Pietsch, C., Mosig, A.S., Wagner, M., Clemens, M.G., Jbeily, N., Koch, N., Gottschaldt, M., Bézière, N., Ermolayev, V., Ntziachristos, V., Popp, J., Kessels, M.M., Qualmann, B., Schubert, U.S., Bauer, M. (2014). Cell type-specific delivery of short interfering RNAs by dye-functionalised theranostic nanoparticles. Nature Communications, 5, 5565. DOI ↗ Wallert, M., Mosig, A.S., Rennert, K., Funke, H., Ristow, M., Pellegrino, R.M., Cruciani, G., Galli, F., Lorkowski, S., Birringer, M. (2014). Long-chain metabolites of α-tocopherol occur in human serum and inhibit macrophage foam cell formation in vitro. Free Radical Biology & Medicine, 68, 43-51. DOI ↗
2013
Liesenfeld, M., Mosig, A.S., Funke, H., Jansen, L., Runnebaum, I.B., Dürst, M., Backsch, C. (2013). SORBS2 and TLR3 induce premature senescence in primary human fibroblasts and keratinocytes. BMC Cancer, 13, 507. DOI ↗
2009
Pottgiesser, T., Schumacher, Y.O., Funke, H., Rennert, K., Baumstark, M.W., Neunuebel, K., Mosig, A.S. (2009). Gene expression in the detection of autologous blood transfusion in sports, a pilot study. Vox Sanguinis, 96(4), 333-336. DOI ↗ Mosig, A.S., Rennert, K., Krause, S., Kzhyshkowska, J., Neunübel, K., Heller, R., Funke, H. (2009). Different functions of monocyte subsets in familial hypercholesterolemia, potential function of CD14+ CD16+ monocytes in detoxification of oxidized LDL. FASEB Journal, 23(3), 866-874. DOI ↗
2008
Mosig, A.S., Rennert, K., Büttner, P., Krause, S., Lütjohann, D., Soufi, M., Heller, R., Funke, H. (2008). Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism. BMC Medical Genomics, 1, 60. DOI ↗
2007
Büttner, P., Mosig, A.S., Funke, H. (2007). Gene expression profiles of T lymphocytes are sensitive to the influence of heavy smoking, a pilot study. Immunogenetics, 59(1), 37-43. DOI ↗ Büttner, P., Mosig, A.S., Lechtermann, A., Funke, H., Mooren, F.C. (2007). Exercise affects the gene expression profiles of human white blood cells. Journal of Applied Physiology, 102(1), 26-36. DOI ↗

Reviews (10)

2025
Koceva, H., Amiratashani, M., Akbarimoghaddam, P., Hoffmann, B., Zhurgenbayeva, G., Gresnigt, M.S., Rossetto Marcelino, V., Eggeling, C., Figge, M.T., João Amorim, M., Mosig, A.S. (2025). Deciphering respiratory viral infections by harnessing organ-on-chip technology to explore the gut-lung axis. Open Biology, 15(3), 240231. DOI ↗ Kaden, T., Alonso-Román, R., Stallhofer, J., Gresnigt, M.S., Hube, B., Mosig, A.S. (2025). Leveraging organ-on-chip models to investigate host-microbiota dynamics and targeted therapies for inflammatory bowel disease. Advanced Healthcare Materials, 14(10), e2402756. DOI ↗
2024
Alonso-Román, R., Mosig, A.S., Figge, M.T., Papenfort, K., Eggeling, C., Schacher, F.H., Hube, B., Gresnigt, M.S. (2024). Organ-on-chip models for infectious disease research. Nature Microbiology, 9(6), 1430 to 1445. DOI ↗
2023
Ney, L.M., Wipplinger, M., Grossmann, M., Engert, N., Wegner, V.D., Mosig, A.S. (2023). Short chain fatty acids, key regulators of the local and systemic immune response in inflammatory diseases and infections. Open Biology, 13(3), 230014. DOI ↗
2022
Shroff, T., Aina, K., Maass, C., Cipriano, M., Lambrecht, J., Tacke, F., Mosig, A.S., Loskill, P. (2022). Studying metabolism with multi-organ chips, new tools for disease modelling, pharmacokinetics and pharmacodynamics. Open Biology, 12(3), 210333. DOI ↗
2021
Lucchetti, M., Kaminska, M., Oluwasegun, A.K., Mosig, A.S., Wilmes, P. (2021). Emulating the gut-liver axis, dissecting the microbiome’s effect on drug metabolism using multiorgan-on-chip models. Current Opinion in Endocrine and Metabolic Research, 18, 94-101. DOI ↗ Siwczak, F., Loffet, E., Kaminska, M., Koceva, H., Mahe, M.M., Mosig, A.S. (2021). Intestinal stem cell-on-chip to study human host-microbiota interaction. Frontiers in Immunology, 12, 798552. DOI ↗ Last, A., Maurer, M., Mosig, A.S., Gresnigt, M.S., Hube, B. (2021). In vitro infection models to study fungal-host interactions. FEMS Microbiology Reviews, 45(5), fuab005. DOI ↗
2019
Raasch, M., Fritsche, E., Kurtz, A., Bauer, M., Mosig, A.S. (2019). Microphysiological systems meet hiPSC technology, new tools for disease modeling of liver infections in basic research and drug development. Advanced Drug Delivery Reviews, 140, 51-67. DOI ↗
2016
Mosig, A.S. (2016). Organ-on-chip models, new opportunities for biomedical research. Future Science OA, 3(2), FSO130. DOI ↗

Book chapters (3)

2026
Koceva, H., Mosig, A.S. (2026). Lung-on-chip systems for infection and inflammation research, platforms, applications, and future directions. In Applications of Microfluidics in Tissue Engineering and Body on Chips, Springer, 2026.
2025
Koceva, H., Mosig, A.S. (2025). Human induced pluripotent stem cell-based alveolus-on-chip model to study influenza virus A infection. In Influenza Virus, Methods and Protocols (Methods in Molecular Biology), 2nd Edition, 2890, 225-235. DOI ↗
2021
Mosig, A.S., Loskill, P. (2021). Organ-on-chip (Kapitel 41). In Lottspeich, Kurreck (Hrsg.), Bioanalytik, Springer Spektrum, 4. Auflage, ISBN 978-3-662-61706-6.